Ibuprofen Comparison – Find the Right NSAID for Your Pain Relief

When working with Ibuprofen, a widely used non‑steroidal anti‑inflammatory drug (NSAID) that eases pain, reduces fever, and lowers inflammation. Also known as Advil, it’s available over the counter in many countries.

It belongs to the broader class of NSAIDs, drugs that block cyclooxygenase enzymes to cut prostaglandin production, thereby diminishing pain and swelling. Popular NSAID cousins include Naproxen, a longer‑acting option often used for arthritis and Arcoxia, the brand name for etoricoxib, a COX‑2 selective NSAID that aims to spare the stomach. Understanding how these agents differ in potency, dosing schedule, and gastrointestinal risk helps you pick the safest fit for everyday aches or occasional flare‑ups.

First, remember that Ibuprofen works best for short‑term pain like headaches, muscle strains, or menstrual cramps, typically at 200‑400 mg every 4‑6 hours. Naproxen, on the other hand, stays in the system longer, so a 250‑mg dose can last 8‑12 hours, making it handy for chronic joint pain. Arcoxia offers even stronger anti‑inflammatory power but carries a higher price tag and a need for prescription in many places because its COX‑2 selectivity can raise cardiovascular concerns. Side‑effect profiles also diverge: ibuprofen may cause mild stomach irritation, naproxen poses a slightly higher ulcer risk with prolonged use, and Arcoxia reduces stomach upset but may increase heart‑related events.

When you compare cost, over‑the‑counter ibuprofen usually wins, especially in generic packs. Naproxen is similarly cheap, while Arcoxia’s brand name version can be pricey, though generic etoricoxib is gradually becoming more affordable. Drug‑interaction checks are crucial—ibuprofen can interfere with blood thinners, naproxen may affect blood pressure meds, and Arcoxia interacts with certain antihypertensives and other COX‑2 inhibitors. By matching your health profile, duration of therapy, and budget, you can decide which NSAID aligns best with your needs. If you’re ready to dive deeper, the articles below break down each drug’s efficacy, safety, and real‑world price points, giving you a side‑by‑side view that makes the choice clear.

Alan Gervasi 12 14 Oct 2025

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